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百癣夏塔热片辅助治疗痤疮的效果

来源:《中国当代医药》 编辑:李伯培 蓝淑婷 时间:2018-10-12

[摘要]目的 探討百癣夏塔热片辅助治疗痤疮的效果及其对患者皮肤屏障功能的修复作用。方法 选取2016年7月~2017年7月佛冈县人民医院收治的100例痤疮患者作为研究对象,采用信封随机分组方法将其分为两组,每组各50例。对照组患者进行红蓝光照射治疗,观察组患者在对照组基础上,给予百癣夏塔热片进行治疗。比较两组患者的临床症状评分、治疗安全性、总有效率、皮肤油脂及表皮水分损失(TEWL)。结果 观察组患者的治疗总有效率高于对照组,差异有统计学意义(P<0.05)。观察组患者的皮损类型、皮损个数、潮红、灼热评分均低于对照组,差异有统计学意义(P<0.05)。观察组患者的皮肤油脂、TEWL、不良反应发生率低于对照组,差异有统计学意义(P<0.05)。结论 对痤疮患者实施百癣夏塔热片治疗,能够降低不良反应发生率,改善潮红、皮损等症状,提升整体疗效,改善皮肤油脂、TEWL。

[关键词]百癣夏塔热片;痤疮;皮肤屏障功能;安全性

[中图分类号] R758.733 [文献标识码] A [文章编号] 1674-4721(2018)5(c)-0084-04

Effects of Baixian Xiatare Tablets in the adjuvant treatment of acne

LI Bo-pei1 LAN Shu-ting2

1.Department of Dermatology,Fogang County People′s Hospital in Qingyuan City,Guangdong Province,Fogang 511600,China;2.Department of Pharmacy,Fogang County Hospital of Prevention and Control of Chronic Diseases in Qingyuan City,Guangdong Province,Fogang 511600,China

[Abstract]Objective To investigate the effects of Baixian Xitare Tablets in the adjuvant treatment of acne and its repair effect of skin barrier function in patients.Methods A total of 100 patients with acne treated in People′s Hospital of Fogang County from July 2016 to July 2017 were selected as the research subjects.They were divided into two groups by the envelope random grouping method,50 cases in each group.The patients in the control group were treated with red and blue light radiation.The patients in the observation group were further given Baixian Xiatare Tablets based on the control group.The clinical symptom scores,treatment safety,total efficacy,skin oils and epidermal water loss (TEWL) were compared between the two groups.Results The total effective rate of treatment in the observation group was higher than that in the control group,and the difference was statistically significant (P<0.05).The types of skin lesions,number of skin lesions,flushing and burning score were of the observation group were all lower than those in the control group,and the differences were statistically significant (P<0.05).The incidence of skin oil,TEWL and adverse reactions in the observation group were lower than those in the control group,and the differences were statistically significant (P<0.05).Conclusion Baixian Xiatare Tablets for the patients with acne can reduce the incidence rate of adverse reactions,improve flushing,skin lesions and other symptoms,improve the overall efficacy,and improve skin oils and TEWL.

[Key words]Baixian Xiatare Tablets;Acne;Skin barrier function;Safety

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